1-atsilgliserin-3-fosfat O-atsiltransferaza

Enzimologiyada 1-atsilgliserol-3-fosfat O-atsiltransferaza (EC)) kimyoviy reaksiyani katalizlovchi ferment hisoblanadi.

asil-CoA + 1-atsil-sn-gliserin 3-fosfat $\rightleftharpoons$ CoA + 1,2-diasil-sn-glitserin 3-fosfat

Shunday qilib, bu fermentning ikkita substrati asil-CoA va 1-atsil-sn-glitserin 3-fosfat, uning ikkita oxirgi mahsuloti esa CoA va 1,2-diatsil-sn-glitserin 3-fosfatdir hisoblanadi.

Ushbu ferment transferazlar oilasiga, xususan, aminoatsil guruhlardan boshqa guruhlarni oʻtkazuvchi asiltransferazalarga tegishli. Ushbu ferment sinfining sistematik nomi asil-CoA: 1-atsil-sn-gliserol-3-fosfat 2-O-atsiltransferazadir boʻlib, umumiy qoʻllaniladigan boshqa nomlar orasida 1-atsil-sn-glisero-3-fosfat asiltransferaza, 1-atsil-sn-glitserin 3-fosfat asiltransferaza, 1-atsilglisero-3-fosfat asiltransferaza, 1 -atsilgliserol-3-fosfat asiltransferaza, 1-atsilglisero-3-fosfat asiltransferaza, asilgliserolfosfataseli va lizofosfatid kislota-atsiltransferaza kabilari ishlatiladi. Bu ferment 3 ta metabolik yoʻlda ishtirok etadi: glitserolipid almashinuvi, glitserofosfolipid almashinuvi va efir lipid almashinuvi .

Manbalar

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